Which drug covers both gram-positive and gram-negative bacteria, as indicated by Polytrim?

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Multiple Choice

Which drug covers both gram-positive and gram-negative bacteria, as indicated by Polytrim?

Explanation:
Two drugs with complementary spectra provide broad coverage against both gram-positive and gram-negative bacteria. Polymyxin B targets and disrupts the outer membrane of gram-negative bacteria, while trimethoprim inhibits bacterial folate synthesis and is active against many gram-positive organisms and some gram-negatives. When combined as Polytrim, these agents cover a wide range of pathogens that can cause conjunctivitis. Therefore, trimethoprim (Polytrim) is the drug that covers both gram-positive and gram-negative bacteria.

Two drugs with complementary spectra provide broad coverage against both gram-positive and gram-negative bacteria. Polymyxin B targets and disrupts the outer membrane of gram-negative bacteria, while trimethoprim inhibits bacterial folate synthesis and is active against many gram-positive organisms and some gram-negatives. When combined as Polytrim, these agents cover a wide range of pathogens that can cause conjunctivitis. Therefore, trimethoprim (Polytrim) is the drug that covers both gram-positive and gram-negative bacteria.

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