The statement about ARBs that is true is which of the following?

The statement about ARBs that is true is which of the following?

• A. They typically do not cause a cough.
• B. They cause a cough in most patients.
• C. They require monitoring for hypokalemia more than other classes.
• D. They are the primary cause of angioedema compared to ACE inhibitors.

Answer: (A)

ARBs differ from ACE inhibitors in that they block the angiotensin II receptor without increasing bradykinin levels. Cough with ACE inhibitors arises from bradykinin buildup in the airway, so ARBs are not typically associated with this cough. That’s why this statement is true. While ARBs can cause hyperkalemia, they do not ordinarily cause hypokalemia, and they are not the primary drivers of angioedema—ACE inhibitors carry that risk more strongly.

ARBs differ from ACE inhibitors in that they block the angiotensin II receptor without increasing bradykinin levels. Cough with ACE inhibitors arises from bradykinin buildup in the airway, so ARBs are not typically associated with this cough. That’s why this statement is true. While ARBs can cause hyperkalemia, they do not ordinarily cause hypokalemia, and they are not the primary drivers of angioedema—ACE inhibitors carry that risk more strongly.