Oral fluoroquinolones are contraindicated in which group?

Oral fluoroquinolones are contraindicated in which group?

• A. Anyone under 18
• B. Adults over 60
• C. People with liver disease
• D. People with kidney stones

Answer: (A)

Focusing on safety in developing bodies explains why this class is avoided in anyone under 18. Oral fluoroquinolones have a known risk of damaging growing cartilage and joints, shown in both animal studies and pediatric reports. This can lead to arthropathy and tendon injuries in children and teens, so these drugs are contraindicated for that age group. In adults, the drugs are used with caution because age can raise risks like tendinopathy or tendon rupture and potential heart rhythm effects, but age itself isn’t an absolute contraindication. Liver disease or kidney stones aren’t universal reasons to stop these medicines; they may require careful choice or dose adjustment rather than outright avoidance.

Focusing on safety in developing bodies explains why this class is avoided in anyone under 18. Oral fluoroquinolones have a known risk of damaging growing cartilage and joints, shown in both animal studies and pediatric reports. This can lead to arthropathy and tendon injuries in children and teens, so these drugs are contraindicated for that age group.

In adults, the drugs are used with caution because age can raise risks like tendinopathy or tendon rupture and potential heart rhythm effects, but age itself isn’t an absolute contraindication. Liver disease or kidney stones aren’t universal reasons to stop these medicines; they may require careful choice or dose adjustment rather than outright avoidance.