Ceftriaxone dosing for gonococcal conjunctivitis is given via which route?

Ceftriaxone dosing for gonococcal conjunctivitis is given via which route?

• A. IM
• B. Oral
• C. Subconjunctival
• D. IV

Answer: (D)

Systemic ceftriaxone is used for gonococcal conjunctivitis, and the preferred route is a single intramuscular dose. Administering ceftriaxone IM achieves rapid, reliable serum and ocular tissue levels to eradicate Neisseria gonorrhoeae from the conjunctiva. Intravenous administration is reserved for disseminated gonococcal infection or more severe disease in a hospital setting, not routine uncomplicated ocular infection. Oral ceftriaxone doesn’t reliably reach therapeutic levels for this purpose, and subconjunctival administration isn’t used. A single 1 g IM dose is the standard approach.

Systemic ceftriaxone is used for gonococcal conjunctivitis, and the preferred route is a single intramuscular dose. Administering ceftriaxone IM achieves rapid, reliable serum and ocular tissue levels to eradicate Neisseria gonorrhoeae from the conjunctiva. Intravenous administration is reserved for disseminated gonococcal infection or more severe disease in a hospital setting, not routine uncomplicated ocular infection. Oral ceftriaxone doesn’t reliably reach therapeutic levels for this purpose, and subconjunctival administration isn’t used. A single 1 g IM dose is the standard approach.