Betaxolol (Betoptic S) is selective for which beta receptor?

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Prepare for the NBEO Part II Test with flashcards and multiple choice questions. Understand the Treatment and Management of Ocular Disease through hints and detailed explanations. Boost your confidence for the exam!

Multiple Choice

Betaxolol (Betoptic S) is selective for which beta receptor?

Explanation:
Betaxolol is selective for beta-1 receptors. This cardioselectivity means it predominantly blocks beta-1 receptors in the heart and in the ciliary body of the eye, where blocking beta-1 reduces aqueous humor production to lower intraocular pressure. Because it spares beta-2 receptors, there’s a lower risk of bronchial side effects compared with non-selective beta-blockers, which would block both beta-1 and beta-2 and can affect the lungs. Beta-3 is not involved in this mechanism.

Betaxolol is selective for beta-1 receptors. This cardioselectivity means it predominantly blocks beta-1 receptors in the heart and in the ciliary body of the eye, where blocking beta-1 reduces aqueous humor production to lower intraocular pressure. Because it spares beta-2 receptors, there’s a lower risk of bronchial side effects compared with non-selective beta-blockers, which would block both beta-1 and beta-2 and can affect the lungs. Beta-3 is not involved in this mechanism.

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